VAC_55_2026 - POSTDOCTORAL RESEARCHER (Blood Stem Cell Identity group)

We are looking for a Junior Postdoctoral Researcher for the Blood Stem Cell Identity group, led by Dr. Vincenzo Calvanese.

Research Description

Hematopoietic stem cells (HSC) are a life‑saving therapy for leukemia and have expanded applications in gene and cell therapy against other cancers, genetic, autoimmune, and infectious diseases. Practical limitations such as donor‑matching or insufficient cell number render these therapies unfeasible or unsuccessful for many patients. This postdoctoral researcher will work on a project aimed at understanding the transcriptional and developmental mechanisms that govern the emergence, self‑renewal and maturation of human HSC, and their relevance for the establishment and maintenance of the leukemia stem cell population in the context of blood cancer. The research will combine directed differentiation of human pluripotent stem cells, in‑vitro and in‑vivo models of human normal and leukemic development, and state‑of‑the‑art ...