Rsch Pro 1-Genetics/Cell Bio - Genetic and Chemical Determinants of Aging

University of Minnesota

📍 United States, Minnesota, United States

Full-time Life Scientists

Job Description

About the Job

The Researcher 1 will work with other lab members to characterize the effects of various genetic manipulations and chemical interventions on worm lifespan and heat stress resistance. In addition, the successful candidate will assist in optimization and validation of the machine-learning assay in other worm phenotypes. 

Principal Duties and Responsibilities:

50% Strain maintenance & life history analysis
Maintain C. elegans strains, perform genetic crosses and characterize life history traits including but not limited to stress resistance and lifespan

20% Routine implementation and development of machine-learning based assays
Carry out compound screens for effects on heat stress resistance. Aid in the development and optimization of new machine-learning based assays.
 

10% Molecular biology
Use PCR for genotyping nematode strains and molecular cloning to generate genetic constructs for introduction into C. ...

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