MacCHESS Staff Scientist

Cornell University

📍 Ithaca, New York, United States

Full-time Life Scientists

Job Description


The Role
The seeks a Ph.D.-level scientist to join the Flexible Macromolecular Crystallography (FlexX) station supporting a vibrant structural biology community. The role blends expert user support for routine and advanced macromolecular crystallography (MX) and collaborative development of new X-ray diffraction capabilities for questions that push beyond standard methods.

Recent FlexX advances—now available to users and still being refined—include fixed-target serial crystallography, support for diffuse scattering experiments, and a diamond anvil cell (DAC) designed for MX.

Priority application areas include:

  • Ambient-temperature crystallography, including serial approaches
  • High-pressure methods (DAC and high-pressure cryocooling), especially to trap intermediates in crystallo
  • Extreme biology conditions (e.g., anoxic, high/low salinity or pH, specific metals)
  • Diffuse...
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