Director, Biologics Formulation Development

About the Company

Dianthus Therapeutics is developing potentially best in class therapies for patients living with severe autoimmune diseases. Their lead candidates focus on extended half-life and improved potency to enable convenient self-administered subcutaneous injections.

Responsibilities

• Lead formulation development strategy for a new bispecific fusion protein from preclinical stage through clinical development
• Design and execute studies to assess protein stability, aggregation, degradation pathways, and viscosity
• Develop liquid and lyophilized formulations to support both IV and SC presentations
• Drive high-concentration formulation development for subcutaneous delivery, including syringeability and device compatibility
• Partner with Analytical Development, Drug Substance, Process Development, Quality, and Regulatory teams
• Collaborate with external CDMOs to ensure alignment between formulation strateg...